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192 However, in another trial conducted by the same research team that included 142 women with osteopenia receiving 800 mg calcium and 1,520 IU (38 mcg) vitamin D daily, the addition of 375 mcg MK-7 daily did not improve bone microarchitecture, BMD, or levels of markers of bone turnover compared with placebo after three years

Oxidative stress represents an imbalance between ROS production and the antioxidant defense system