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BoeschSaadatmandi C, Wagner AE, Graeser AC, Hundhausen C, Wolffram S, Rimbach G
FASEB J 19:15046, PMID: 15972297 Kanno T, Nishizaki T (2001) Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c

Neither has reached a clear plateau in the published trial windows

Research demonstrates BPC-157 enhances growth hormone receptor expression in tendon fibroblasts by 7 within 3 days, supporting tissue repair signaling cascades