glutathione homocysteine metabolism metabolism. The sulfur-containing amino acid methionine is Glutathione Metabolism - an overview

p=0.003) Discussion Since the first report of the neurotoxicity of the copper chelator cuprizone in Swiss albino mice by Carlton in 1966 (Carlton, 1966) and the subsequent early description of CPZ-induced OL death and demyelination in the superior cerebellar peduncles of ICI mice (Blakemore, 1972), the CPZ-induced demyelination model has been intensively studied and optimized for more than five decades (Vega-Riquer et al., 2019)

Instead, the disease and context specific loss or disruption of astrocyte functions can result in the accumulation of various potentially toxic metabolites or in the loss of support functions for neurones or synapses or in (the deadliest) combination of both

doi: 10.1111/sms.12581

references in Table 1 )