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Similar to other lipids, PEG-lipids have a hydrophobic portion that is usually made of alkyl chains, which is integrated into the lipid layer, and a hydrophilic part that also contains the PEG, which extends from the surface of the LNPs
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Kimura KD, Tissenbaum HA, Liu YX, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
