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The enzymatic activity of SIRTs is dependent on NAD + as a cofactor and plays an important role in controlling gene expression, DNA repair, metabolism, oxidative stress response, mitochondrial function, and biogenesis

Analysis of glutathione levels in the brain tissue samples from HIV-1-positive individuals and subject with Alzheimers disease and its implication in the pathophysiology of the disease process

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Hess D.T., Stamler J.S

The list of drug targets was compiled after combining the outputs of SuperPred and SwissTargetPrediction and removing duplicates, and used as Set A, while epilepsy genes were used as Set B and oxidative stress-related genes were used as Set C