novo nordisk cagrilintide shares plunge after CagriSema obesity drug trial disappoints Semaglutide, a glucagon-like peptide-1 (GLP-1)

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Sikiric, et al, demonstrated its possible use to heal distended stomachs and noted that it has been used safely and with some effect in trials for irritable bowel disease

While animal studies extending to 6 weeks have found no concerning signals, humans using the peptide are essentially participating in uncontrolled self-experimentation regarding long-term outcomes

doi: 10.1136/bmj.b2535