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To explore the role of p38 MAPK in ferroptosis-induced VEGFA and IL8 induction, ESCs were treated with erastin in the absence or presence of the p38 inhibitor, SB203580 (10 M) for 12 h
doi: 10.3390/ma13184127
One study showed that ROS-mediated modification of residues of cysteine 257, 268, and 586 can lead to the formation of an intramolecular disulfide bond on RIP1, which promotes the autophosphorylation of RIP1 at serine 161 thereby effectively recruiting RIP3
Circulation 100 , 12741279 (1999)
