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Iron overload can lead to diabetes symptoms such as decreased insulin secretion, metabolic abnormalities, and mitochondrial dysfunction (Huang et al., 2013), and accelerate the development of diabetes with prompting cell dysfunction (Utzschneider et al., 2014)

However, this task is currently facilitated by the availability of data derived from the application of available omics and other approaches, which can provide information on vaccine-targetable proteins that are exposed to the effectors of the immune system and may play key roles in the pathogens biology

In this context, the investigation employed A2780 and IGROV1 cells, along with their cisplatin-resistant counterparts, A2780/CP70 and IGROV1-R10, to explore SFNs potential in overcoming cisplatin resistance