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As of early 2021, neither medication is approved for any indication in the United States
the tonicity is preferably from half to twice as high as that of physiological saline, more preferably from three-quarters to one and a half as high as that of physiological saline
Current areas of scientific investigation include telomere-associated pathway analysis, cellular aging and replication signaling studies, transcriptional and epigenetic regulation research, circadian and pineal-associated signaling investigations, genomic stability pathway research, and intracellular signaling network evaluation
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