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Due to the high absorption and low metabolism characteristics of tumor tissue, photosensitizers can specifically accumulate within tumors, then activated by a specific wavelength laser, catalyzing a series of chemical reactions to produce reactive oxygen species, ultimately inducing tumor cell death (140)

The rats were given daily injections of tesofensine plus a fixed dose of 5-HTP (31 mg/kg, i.p.) and CB (75 mg/kg, i.p.) for 15 days, following one of six protocols: vehicle (control, n = 6 for each group), 5-HTP/CB (31 and 75 mg/kg), tesofensine1 (1 mg/kg, s.c.), tesofensine2 (2 mg/kg, s.c.), tesofensine1 + 5-HTP/CB, and tesofensine2 + 5-HTP/CB

Lean meats and seafood can be great options for those looking to enjoy flavorful and satisfying meals without the worry of heartburn

Ann Oncol 35(11):1003-1014, 2024