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Gastrointestinal disorders such as celiac disease, Crohn's disease, or surgical removal of parts of the digestive tract can also impair B12 absorption

It is also worth noting that -lipoic acid, a metabolite in the cuproptosis pathway, has shown promising results in both cell-based and animal models of Wilsons disease

Step 2 To a solution of compound 1b (257 mg) in acetic acid (5 mL) was added zinc powder (339 mg) in batches