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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

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Dysregulation of the copper transport system may be potentially toxic in the cuprizone model, as stimulating CTR1 expression in astrocytes along with high copper stimulus in vitro primes astrocytes such that once they return to basal conditions, they release factorspossibly copperthat are toxic to oligodendrocytes [180]

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