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Below are important risk factors for hypothyroidism to be aware of

Figure 1 Funding This work was funded by the National Natural Science Funds of China (82074234 and 82071756), National Key Research and Development Project (2018YFC1705200 and 2018YFC1705203), Shanghai Chinese Medicine Development Office, National Administration of Traditional Chinese Medicine, Regional Chinese Medicine (Specialist) Diagnosis and Treatment Center Construction Project-Rheumatology, State Administration of Traditional Chinese Medicine, National TCM Evidence-Based Medicine Research and Construction Project, Basic TCM Evidence-Based Capacity Development Program, Shanghai Municipal Health Commission, and East China Region-based Chinese and Western Medicine Joint Disease Specialist Alliance

Healthy mammalian tissues have a cytoplasmic ratio of free NAD+ to NADH at about 700:1, which creates ideal conditions for oxidative reactions

Converted to active calcitriol, it regulates calcium and phosphate
