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3, the inhibitors targeting NADPH-synthesis enzymes are being extensively developed

The pathogenesis involves a type IV hypersensitivity reaction where the drug acts as a hapten, binding to tubular cells and inducing a T-cell-mediated immune response

That very strange meeting, which happened to take place at Hys, forms the basis of the final chapter of this story

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Shoseyov D., Bibi H., Biesalski H., Reifen R