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doi: 10.1038/onc.2010.215
J Clin Child Adolesc Psychol
Although the precise role of ferroptosis in the pathogenesis of HH remains unclear, recent research suggests that it may be involved in the pathological processes of HH [234]
Activation of the SIRT1/Nrf2 pathway, such as by alpha lipoic acid, can modulate iron metabolism and mitigate ferroptosis by up-regulating ferritin and ferritin heavy chain 1 (FTH1), and down-regulating the iron import protein divalent metal transporter 1 (DMT1) (Zheng et al., 2023)
