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10.1038/ng1098 14

481 In addition, meta-analyses of trials involving subjects with acute coronary syndrome (a cardiac emergency involving blocked coronary circulation, such as heart attack or unstable angina) have also found no cardiovascular or mortality benefits from including colchicine in secondary prevention

It was first developed in 1991 as a derivative of Body Protection Compound, a peptide naturally found in human gastric juices [1, 2]
