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Another consequence of UPR is the activation of SREBP-1c pathways, which results in the maintenance of liver fat accumulation and a further exacerbation of ER stress and UPR ( 3 CHM used in treatment for NAFLD NAFLD is a complex metabolic disorder that often co-occurs with other metabolic conditions such as dyslipidemia, hypertension, and diabetes mellitus (Zhao et al., 2018)
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Diabetes 37 , 10201024 (1988)
