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Their purpose appears to be to return pHi to slightly alkaline values that are more favorable to cell survival and proliferation
(2024) 16:eadk8230

in its active form (thiamine diphosphate), it is an essential cofactor for enzymes in glucose and amino acid catabolism, helping convert nutrients into ATP and supporting normal neuronal function

A role for extracellular Na+ in the channel gating of native and recombinant kainate receptors
