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All nonvitamin nutritional supplements (including amino acid, protein, or antioxidant supplements) and lipid-lowering medications were stopped from 4-weeks prior to laboratory tests until the end of the study to avoid any confounding effects on mitochondrial function

Diabetes 47 , 17791785 (1998)

When GLP-1 is secreted from L-cells through the TGR5 agonist, it stimulates GLP-1R in enterochromaffin cells and induces serotonin or 5-hydroxytryptamine (5-HT) secretion from these cells

Notably, the WYRGRL-targeted fluorescent nanoparticles exhibited a 72-fold higher signal after 48 h compared with nanoparticles comprising a scrambled peptide