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[The question] is just whether or not increasing them synthetically is safe or not. There are several well-studied, FDA-approved peptides available today, such as insulin and GLP-1s like Ozempic and Wegovy, but thats just a sliver of the peptide pie

Active, uncontrolled thyrotoxicosis from Graves disease, toxic multinodular goiter, or factitious intake also precludes administration, as additional T3 would intensify hyper-metabolic sequelae

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Their mechanisms are complementary rather than competitive, addressing different aspects of neural plasticity: Dihexa promotes the structural formation of new synaptic connections, while PE-22-28 enhances neuronal excitability and drives neurogenesis