is trulicity a glp 1 drug Lilly's Easy-to Use Once-Weekly GLP-1 Agonist Approved in Europe Trulicity (dulaglutide): Injectable GLP-1 RA

These agents include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)

doi: 10.1016/S0140-6736(21)01443-4

Roche Holding AG Roche contributes through diagnostics and personalized medicine initiatives that complement GLP-1 therapy, helping optimize treatment strategies for obesity and diabetes

The primary mechanisms of action include: Enhancing glucose-dependent insulin secretion from pancreatic beta cells, which helps lower blood glucose levels when they are elevated Suppressing glucagon release from pancreatic alpha cells, reducing hepatic glucose production [1] [2] Slowing gastric emptying , which moderates the rate at which nutrients enter the bloodstream Promoting satiety through central nervous system pathways, leading to reduced caloric intake [1] [2] These medications are peptide-based (and one fusion protein) and are temperature sensitive