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Description
Polyunsaturated fatty acids (PUFAs) are sensitive to lipid peroxidation and are one of the essential elements for ferroptosis 29

IGF-1 is the downstream effector produced primarily by the liver in response to GH

The combination also preserves the physiological pulsatile pattern of GH release, as both pathways remain subject to somatostatin feedback
10.1093/oxfordjournals.humrep.a136893 23
