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In MPTP animals, depletion of HexCer(t42:2), SHexCer(t43:2), and SM(d43:2) and an increase in SHexCer(d40:1) in the GPi and GPe correlated significantly with DAT scores in the Cd and Put (Supplementary Figs

Five distinct clusters of diabetes have been proposed, of which mild age-related diabetes is the most common, making up 40% of diabetes diagnoses, and is directly attributable to ageing-related ectopic fat deposition and insulin resistance [26]

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