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Acute diarrhea may also present with abrupt onset of nausea, vomiting, abdominal pain, headache, fever, chills, and malaise

We previously identified a novel Cu/Zn SOD from jellyfish Cyanea capillata , named CcSOD1, and confirmed its specific SOD activity 19

This gene is present in its homozygous form in about 10% of most European populations
Therefore, chronic stress-induced dysregulation of the HPA axis, potentially mediated by imbalances in gut microbiota, might be a crucial link between dysbiosis and the progression of AD (Figure 1)
