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Although in many individuals with PVOL the evolution occurs relatively quickly and spontaneously, in a significant number of patients the partial or total loss of the sense of smell has been shown to be persistent
Free Radic Biol Med 42:617626 de Bernardo S, Canals S, Casarejos MJ, Solano RM, Menendez J, Mena MA (2004) Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures
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