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& Kumar, S

The thyroid hormone receptor variant 2 is a weak antagonist because it is deficient in interactions with nuclear receptor corepressors 1

Figure 2 gives an overview of some of the pathophysiological mechanisms implicating the detrimental effects of oxidative stress and inflammation in conditions of diabetes or related metabolic complications

Therefore, further studies in humans are needed in order to evaluate the efficacy of these phytochemicals and their feasibility as a natural substitute for pharmaceutical agents, many of which are associated with adverse side effects
