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Chronic stress, alcohol, poor sleep, and inflammation accelerate this depletion

doi: 10.1038/s41598-024-75286-4 23

pylori colonization also negatively affects the expression of antioxidant proteins, along with epigenetic modifications and DNA methylation, such as GATA-4, GATA-5 and TWIST-1 (88), as well as miRNAs dysregulation, such as mir-21, mir-92a, mir-27a, mir-146a, mir-326, mir-155 and mir-663 (73, 89)

J Bacteriol 1999