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best place to give im b12 injection Shots at Home: How, Where & How Often Inject Yourself How to self-inject intramuscular vitamin
Description
One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12

How much reduced depends on your genotype: If you are heterozygous (CT one copy of the variant): your MTHFR enzyme retains approximately 65% of normal activity [3, 4]
Both of these changes disappeared by the second cycle post-vaccination
Any discomfort is brief and typically fades within moments
