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Hydrophobicity, size, and complementarity all substantially contribute to differential binding affinity and to the selective high-affinity binding of the AR AF2 to phenylalanines at the +1 and +5 positions in coactivator recognition helices

Double-shear connections provide incredible strength and impact resistance

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Butyrate is considered the primary energy source for colonic epithelial cells, and its deficiency has been associated with the development of colitis and cancer (68)