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Description
Depletion of bioavailable nitric oxide in the vasculature by excess oxidants causes endothelial dysfunction, which is characterized by a decrease in endothelium-dependent vasodilation while retaining the ability of vascular smooth muscle cells to vasodilate in response to nitric oxide donors, such as sodium nitroprusside [53]

Undoubtedly, the members of glutathione transferase family play an important role in metabolism of certain therapeutics, detoxification of environmental carcinogens and reactive intermediates formed from various chemicals by other xenobioticmetabolising enzymes
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Zhou Y, Fan X, Jiao T, Li W, Chen P, Jiang Y, et al
