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Instead of asking which is better, a better question is how to support both systems in a smart, sustainable way

Pro-inflammatory microglia drive tau proliferation and toxicity by promoting neuroinflammation, such as activation of NLRP3 inflammasomes or induction of NF-kB signaling (23)

doi: 10.1021/acs.jafc.5b00556

Certain reactive oxygen species, such as hydrogen peroxide, are also essential for growth factor-mediated signal transduction, mitochondrial function, and maintenance of normal thiol redox-balance
