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Together, these results reveal mechanistic details of the SBS-PolkKO mutations and underscore the fact that mutational signatures are complex patterns jointly shaped by the nature of the DNA lesion and the interplay of DNA repair and lesion bypass processes
2020;2(S1):S54-65
The result is normally a gelatinous, nutritious, rich stock that can be sipped or added to foods
These factors collectively contribute to the progressive decline in chondrocyte function and accelerated breakdown and loss of ECM(2)
