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1 Introduction Metabolic syndrome (MetS) constitutes a multifaceted array of metabolic disorders, manifesting as disturbances in the bodys handling of energy substrates, including proteins, fats, and carbohydrates

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Identification of novel human nicotinamide N-methyltransferase inhibitors: a structure-based pharmacophore modeling and molecular dynamics approach

[1] The authors framed the observed metabolic shifts as a direct effect on lipid handling in the model rather than appetite suppression