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In contrast, KI mice showed no detectable abnormalities in the open field test (Additional file 1: Fig

Pharmacologic and Toxicologic Profile of Chymopapain B (Chemolase)

Because so many people worldwide suffer from seizure disorders and there are so few effective treatments available, this condition is regarded as a major health problem

While proteasomes target and selectively degrade ubiquitinated proteins, autophagy degrades all the contents engulfed by autophagosomes, and, therefore, is called the bulk degradation system. In addition, selective autophagy pathways target cellular organelles, such as mitochondria and peroxisomes