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Activity of EGFR inhibition in atypical (non-V600E) BRAF-mutated metastatic colorectal cancer

They enter the cell, reach the nucleus, and interact with chromatin, the complex of DNA and histone proteins that determines which genes are accessible for transcription

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10.1158/1078-0432.CCR-04-0812 25 BergersG.HanahanD
