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In the transformation of hemorrhage after cerebral ischemia, iron overload significantly decreases oxidation metabolism, lactic acid generation, and brain pH value, further increasing iron release
Zhao, Development of high-drug-loading nanoparticles

PMID: 28002875 Chiew AL, Isbister GK, Kirby KA, et al

10.1126/SCIENCE.274.5287.546
