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Cadmium-induced hepatotoxicity in mice - prophylactic supplementation of quercetin exerts hepatoprotective effect by modulating PI3K/Akt/NF-kappaB signaling pathway

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Specifically, one double-blind trial in 140 patients with chronic schizophrenia, described by the Cochrane Collaboration as a high quality trial that measured clinically-useful outcomes (Positive and Negative Syndrome Scale [PANSS] and Clinical Global Impression [CGI]) over a longer period of time [145], compared adjunctive NAC versus placebo [146]