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Conversely, cardiac disorders, such as myocardial infarction, heart failure, and atrial fibrillation can adversely impact brain structure and function These effects are mediated through shared mechanisms, including systemic inflammation, cerebral hypoperfusion, thromboembolism, and microvascular dysfunction, resulting in neurological complications such as ischemic stroke and cognitive decline

To achieve blood levels of at least 30 ng/mL, adults living at temperate latitudes (think: anywhere with distinct seasons) need 800 to 1,000 IU per day, ideally from vitamin D3, which is more effective than D2

Oxidative stress induced sperm DNA damage, a possible reason for male infertility

doi: 10.2460/javma.255.5.546 13