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Given that the mammalian m 6 A reader YTHDC1 associates with components of the nuclear exosome targeting complex and is involved in retrotransposon RNA degradation 15 , we performed yeast two-hybrid (Y2H) assays and found that CPSF30-L does not directly interact with the nuclear exosome targeting components ZCCHC8A, ZCCHC8B and RBM7 (Supplementary Fig

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