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However, where more than one therapeutic approach was applied, such as an adjunctive immune modulator, intravesical injection, intravesical instillation with BTX or HA, or HA and CS, or changes in diet, more positive outcomes could be anticipated which could be demonstrated in the future by RCTs

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The use of hydroxocobalamin in cats has been described [86], and it appears to be effective in restoring cobalamin to normal ranges

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