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Conclusion Building on decades of research, the last 5 years have seen a flurry of novel discoveries enabled mostly by three key developments: (1) multi-omics approaches that integrate genetic, epigenetic, transcriptomic and proteomic profiling alongside high-resolution imaging and functional studies

Using gene editing tools such as CRISPR/Cas9, researchers can knock out key genes like PHGDH to directly regulate serine synthesis at the genetic level

Water Makes up about 97-98% of bile and acts as the liquid base that dissolves the other ingredients

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