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It should be mentioned that the presence of immune cells in the damaged tissues is a typical feature of postischemic revascularization [47]

Fenton reaction (an oxidation process that generates hydroxyl radicals using hydrogen peroxide and ferrous ions) and breakdown of lipid-derived radicals contribute to cellular oxidative stress ( Ferroptosis has been recently investigated as one of the iron-dependent mechanisms that most intervene in cell death in metabolic dysfunctions and PD

doi: 10.1001/jama.2017.6803

Chronic conditions may benefit from extended treatment periods of 3-6 months, followed by maintenance dosing or cycling protocols