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they are continually absorbing small quantities from their air, water, food, bedding, soil, lawns, cleaning agents, and veterinary pharmacologic treatments

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The superoxide dismutase family is composed of manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix, as well as Cu,Zn superoxide dismutase (SOD1) located in the mitochondrial intermembrane space, cytosol, and extracellular space