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The proportion of p--syn in the normal state is very low, and an abnormal increase in p--syn induces the formation of pathological aggregates that contribute to neurotoxicity [10]
Wynn, T
The Phase IIb efficacy trials did not meet their efficacy endpoints, and clinical development for the original therapeutic indication was halted
Unlike compounded drugs, counterfeit drugs could contain the wrong ingredients, contain too little, too much, or no active ingredient at all, or other harmful ingredients, and are illegal, the FDA said
