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Cost and Manufacturing Complexity The manufacturing costs of peptide drugs are generally higher than small molecule medications due to more complex synthesis or production processes

2.1 Liquid-liquid phase separation drives -synuclein fibrillation Liquid-liquid phase separation (LLPS) is a physical phenomenon which involves separation of a uniform solution of macromolecules into two distinct liquid phases with different densities of macromolecules, resulting in the formation of coacervate like structures

[DOI] [PMC free article] [PubMed] [Google Scholar] 122.McCrea H.J., Ivanidze J., OConnor A., Hersh E.H., Boockvar J.A., Gobin Y.P., Knopman J., Greenfield J.P

In research models the two molecules act on parallel pathways of the growth hormone axis