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413 Partial ablation of astrocytes in the prefrontal cortex of healthy rats (by injection of gliotoxin L--aminoadipic acid) resulted in the development of depressive-like behaviours, whereas injection of neurotoxin ibotenate did not have such an effect

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As an illustration, it opposed hypertension and pro-thrombotic effects (L-NAME) [11,29,97,98,99], as well as hypotension and anti-thrombotic (L-arginine) effects [11,29,97,98,99]

Additionally, a variety of molecular methodologies were utilized, including Western blotting, reverse transcription, quantitative PCR, immunofluorescence, and immunohistochemistry