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Morphological analysis revealed marked structural disruption, including cell disaggregation, loss of spheroid organization, and destruction of the outer proliferative layers, supporting its cytotoxic activity in three-dimensional culture

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The following formula illustrates the relationship: Concentration (mg/mL) = Vial content (mg) Volume of bacteriostatic water added (mL) Illustrative examples: 2 mg vial + 1 mL bacteriostatic water = 2 mg/mL 2 mg vial + 2 mL bacteriostatic water = 1 mg/mL 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL Note that the concentrations in the examples above differ from one another

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