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Additionally, Nrf2 knockout mice are more sensitive to mitochondrial complex inhibitors such as MPTP and 3-nitropropionic acid [108], suggesting an important role of this transcription factor in scavenging free radicals

All patients in the intervention arm attained mTICI 3 recanalization, although this distinction did not achieve statistical significance ( p = 0.53)
it decreases to 70% for the second stage, 58% for stage III, and fewer than 15% for stage IV (128)

PMID: 78 JeongJChaoCJArsanjaniRAyoubCLesterSJPereyraMet al
