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doi: 10.1016/j.freeradbiomed.2009.07.023 34 SainiRSinghS

It is important to note that Epitalon showed a more prolonged mechanism of action than Vilon and was significantly more potent after three hours of the experiment [22]

Melatonin also exerts antiestrogenic activity, which is particularly significant in hormone-dependent tumors, regulating the expression and transactivation of the estrogen receptor, and modulating the enzymes involved in the local synthesis of estrogens