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Prior work supports the principle that post-stroke microbiota states can influence neuroinflammation, consistent with a closed pathogenic loop that warrants targeted efforts to interrupt braingut feedback (

10.1016/j.envexpbot.2013.12.006 17 KhanI.AhmadA.IqbalM

28 , 29 As such, the pH of a topically applied cosmetic such as a sunless tanning product must be carefully considered so as to not disrupt the pH balance of the SC